Ruxolitinib found to cause eyelash growth : a case report

Journal of Medical Case Reports

Hypereosinophilic syndrome (HES) is a rare hematologicdisorder in which the eosinophils proliferate. The eosino-phils infiltrate and damage multiple organs. Without treat-ment, the condition is fatal, usually due to cardiacdysfunction, particularly left ventricular dysfunction.Causes of reactive eosinophilia include allergic and hyper-sensitivity reactions, drug allergies, cytokine therapy (re-combinant human interleukin), cutaneous disorders,connective tissue diseases, collagen vascular disorders,parasitic infections, immunodeficiency disorders, sarcoid-osis, and neoplasms, such as Hodgkin’s and non-Hodgkin’s lymphomas and acute lymphoplastic leukemia.Various hematopoietic neoplasms that demonstrate bloodeosinophilis are B cell and T cell non-Hodgkin’s lymph-omas, chronic myeloproliferative disorders (chronic:chronic myelogenous leukemia, chronic eosinophilicleukemia, systemic mast cell disease; acute: acute myeo-monocytic leukemia (AML) with eosinophilia, acutelymphoblastic leukemia with eosinophilia, and other mye-loid leukemias).Ruxolitinib is approved for myelofibrosis (MF) and iseffective in reducing splenomegaly. The medication isoff-labe l for HES but has been reported to be successfulin eosinophilic leukemia. Ruxolitinib (Jakafi®) has beenreported to aid in refractory alopecia areata. Our patientnoted that his eyelashes grew significantly. This is thefirst case in which eyelash growth has been reported. [..more]

Complications of selective laser trabeculoplasty: a review

Julia Song Ophthalmology, Long Beach Memorial Medical Center, Long Beach, CA, USA Abstract: Selective laser trabeculoplasty is a laser treatment to treat glaucoma. It was initially indicated for open-angle glaucoma but has been proven to be efficacious for various types of glaucoma. This review article summarizes the few rare complications that can be seen with selective laser trabeculoplasty. It also makes recommendations on how to avoid these problems and how to treat patients when these rare complications arise.
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